RHEUMATOID ARTHRITIS
DEFINITION:-
Rheumatoid
arthritis is a progressive and persistent type of polyarthritis that starts in
the peripheral joints but later involves almost all the joints of the body, bilaterally
and symmetrically causing permanent disability and invalidism.
CAUSES 0R AETIOLOGY:-
-
Auto immune disorder.
Some of predisposing factors are
-
Age - 30-40 years.
-
Sex – 3-4 times more common in females.
-
Climate – more common climates are cold, damp
and fog.
-
Heredity – family history of the disease may be
obtained in some cases but not in all cases.
PATHOLOGY:-
The
pathological changes are progressive and irreversible. The synovial membrane is
involved first. The membrane becomes more vascular, swollen and hypertrophied,
the membrane and the underlying connective tissue is infiltrated with
lymphocytes (esp T lymphocytes), plasma cells and macrophages. At this stage
there may be effusion into the joint space. A circular ridge of granulation tissue
forms at the periphery which later invades the articular cartilage (pannus
formation) and causes its destruction, this is followed by fibrous adhesions
resulting in fibrous ankylosis.bony ankylosis occurs still later. In advanced
cases osteoporotic changes occur in the adjoining bones along with wasting of
the muscles and atrophy of the overlying skin. Rheumatoid nodules seen in subcutaneous
tissue, immunological damage to small sized arteries is responsible for severe
systemic features of the disease. That it is a systemic disorder of the
connective tissue is evident by the fact that lesions also occur in the pleura,
lungs, heart and the sclera.
SYMPTOMS:-
-
Pain is more on night.
-
Swelling of all over the joints.
-
Morning stiffness of all joints.
-
Hands show the typical table fork deformity.
-
Restricted movements of all joints.
-
Malaise, tiredness, loss of weight.
-
Numbness and tingling in the limbs.
-
Vague pain in the muscles and joints.
-
Low grade fever.
-
Other non – articular involvements include
pleural effusion, scleritis, episcleritis, arteritis, peripheral neuropathy and
myopathy.
INVESTIGATIONS:-
-
ESR – ESR is consistently high, much above the normal
value.
-
Agglutination test.
-
C-reactive protein test.
-
Examination of synovial fluid.
-
Radiology – x ray.
COMPLICATIONS:-
1.
Tendinitis, rupture of tendons and rupture of
the joint capsule.
2.
Local nerve compression occurs in carpal-tunnel
syndrome.
3.
Septic arthritis, more likely to occur during
steroid therapy.
4.
Refractory anemia.
5.
Myelopathy when cervical spine is involved.
6.
Secondary amyloidosis
TREATMENT:-
1.
Rest - during acute stage the patient should be given complete rest
for 2-3 weeks.
2.
Use of anti inflammatory drugs – like aspirin,
ibuprofen, ketoprofen, fenoprofun, diclofenac etc.
3.
Physiotherapy.
4.
Surgical measures.
DIET:-
-
Rich in vitamins
food like milk, eggs,
-
Rich in iron food.
-
Avoid potato, beetroot.
-
Avoid alcohol and cigarette smoking.
HOMEOPATHIC REMEDIES:-
1.
ARNICA:-
Limbs and body ache as if beaten; joints as if sprained. Bed feels too
hard, chilly patient, Nervous; cannot bear pain; whole body oversensitive. Great
fear of being touched or approached. Pain in back and limbs, as if bruised or
beaten. Cannot walk erect, on account of bruised pain in pelvic region. Rheumatism
begins low down and works up. [Ledum.]. Even its very good remedy for any
injury.
2.
ACTACEA SPICATA:-
Sharp rheumatic pains in small joints. Wrist ankles and toes. Swelling of
joints from slightest fatigue. The wrist is swollen, red and is worse by any
motion. There is sudden lassitude after talking or eating.
3.
CAULOPHYLLUM:-
It is one of the best remedies for small joint affections when there are
sharp needle like prickling pains which
constantly shift from one place to another. There are cutting pains on closing
the hands. In females, it may be associated with rigid os and severe pains during
menses. All the complaints are made worse from motion.
4.
COLCHICUM:-
Sharp pain down left arm. Tearing in limbs during warm weather, stinging
during cold. Pins and needles in hands and wrists, fingertips numb. Limbs,
lame, weak, tingling. Pain worse in evening and warm weather. Joints stiff and
feverish; shifting rheumatism; pains worse at night. Oedematous swelling and
coldness of legs and feet. Tingling in the finger nails.
5.
DULCAMARA:-
The rheumatic troubles induced by damp cold are aggravated by every cold
change and somewhat relieved by moving about. Rheumatism alternates with
diarrhoea. Rheumatic symptoms after acute skin eruptions. Pain in shin-bones. Perspiration
on palms of hands. Paralysis; paralyzed limbs, feet icy cold.
6.
GUAICUM OFFCINALE:-
Rheumatic pain in shoulders, arms and hands. Growing pains. [Phos. ac.].Gouty
tearing, with contractions. Immovable stiffness. Ankle pain extending up the
leg, causing lameness. Joints swollen, painful, and intolerant of pressure; can
bear no heat. Stinging pain in limbs. Arthritic lancinations followed by
contraction of limbs. A feeling of heat in the affected limbs. Worse; from
motion, heat, cold wet weather; pressure, touch, from 6 pm to 4 am. Better; external pressure.
7.
KALI IODOM:-
Shoulders: tearing in left; in right, then
in right ear; pain in tendons of right on motion, touch, and rest, like a
tension and as if swollen; bruised pain in left; paralytic pain only on moving
them. Tearing twitching in right knee. Painful drawing in calves when sitting.
Tearing in back part of left heel when sitting; in right heel when standing,
>walking. Tearing in great toes; in right second toe.
8.
PULSATILLA:-
It is a good remedy for arthritis of the small joints when pains are
sharp and constantly shifting and changing place from one to another. The pain
is associated with chillness. They are better by motion and in open air, hot
patient, thirstless.Knees swollen, with tearing, drawing pains. Drawing,
tensive pain in thighs and legs, with restlessness, sleeplessness and
chilliness. Boring pain in heels toward evening; suffering worse from letting
the affected limb hang down. [Vipera.].
9.
VIOLA ODORATA:-
It is a good remedy for rheumatism of the small joints specially with a
pressing pain in right carpel and metacarpal joint. It is associated with milky
urine which smells strong. The complaints are worse from cool air.
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